Introduction to BioXmark®

BioXmark® is a liquid fiducial marker with unique features to enhance target visibility on imaging and enable high precision radiation therapy.

 

See below for a video introduction to BioXmark®, including application and features of the product:

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BioXmark® is compatible with both conventional Image-guided Radiation Therapy (IGRT) and Proton-Beam Therapy (PBT) and a tool to empower healthcare professionals to continuously improve the treatment of cancer patients.

 

See also our BioXmark brochure:

BioXmark® has the following main features and benefits:

 

Customizable implantation

  • The liquid nature of BioXmark® enables implantation of multiple size-adaptable markers in the same procedure
  • BioXmark® can be implanted with standard equipment, including thin needles (≥ 25G) and flexible scopes – guided visually, by fluoroscopy and/or ultrasound with a low risk of complications

Positional stability and visibility

  • After implantation of BioXmark®, sticky and soft markers are formed in vivo, adaptive to the surrounding tissue
  • BioXmark® contains a proprietary iodine-based contrast agent to ensure marker visibility on relevant imaging modalities, including X-ray (2D X-ray, fluoroscopy, CT and CBCT), ultrasound and MRI
  • BioXmark® markers are positionally stable and visible during treatment planning, treatment and follow-up

Photon and proton radiation compatibility

  • BioXmark® markers are non-metallic and have a low level of artifacts, supporting precise treatment planning and image guided treatment
  • The low level of artifacts and visibility on CT and MRI facilitates fusion of CT and MRI for better treat-ment planning
  • BioXmark® has low dose perturbation and is compatible with proton therapy

 

For more information on BioXmark® see Features & benefits

BioXmark® features are documented in three white papers:

For further details about the use of BioXmark® – please see Instructions for use (IFU), which are available for download in 10 language versions.