Features & benefits
The main features of BioXmark® are:
• Liquid
• Highly viscous gel-like marker upon injection
• Patented iodine compound
• Non metallic
Feature: Liquid
Claim Benefit
Injectable with thin needles up to 25G Less risk for procedure related complications
such as bleeding and pneumothorax
Adaptable marker sizes Meeting different needs for marker sizing.
Adaptable also during implantation
Implantation of multiple markers in the same procedure Less risk of procedure related complications
Applicable in soft tissue including organs in the
thoracic, pelvic and abdominal regions One marker to cover a wide range of cancers
such as lung, esophagus, rectum and bladder cancer
Implantable with flexible scopes Implantation with flexible scopes gives
accessibility across multiple cancer locations
Implantable with standard equipment No need for additional training nor for special equipment
Fast and easy implantation procedure Potential to save time
| Claim | Benefit |
|---|---|
| Injectable with thin needles up to 25G | Less risk for procedure related complications such as bleeding and pneumothorax |
| Adaptable marker sizes | Meeting different needs for marker sizing. Adaptable also during implantation |
| Implantation of multiple markers in the same procedure | Less risk of procedure related complications |
| Applicable in soft tissue including organs in the thoracic, pelvic and abdominal regions | One marker to cover a wide range of cancers such as lung, esophagus, rectum and bladder cancer |
| Implantable with flexible scopes | Implantation with flexible scopes gives accessibility across multiple cancer locations |
| Implantable with standard equipment | No need for additional training nor for special equipment |
| Fast and easy implantation procedure | Potential to save time |
Feature: Sticky and soft iodine-based marker
Claim Benefit
Biocompatible Has an acceptable biological safety profile
Adaptive to surrounding tissue Low risk of tissue damage
Positionally stable during
treatment planning, treatment and follow-up Enables precise target localization during
treatment planning, treatment and follow-up
Visible on ultrasound Ultrasound guided implantation ensures higher precision of
marker placement and verification of marker location
Radiopaque, visible on X-ray (2D X-ray, fluoroscopy, CT, CBCT) Visibility on X-ray enables high precision
in treatment planning, treatment and follow-up
Fluoroscopy guided implantation ensures higher precision during
marker placement and verification of marker location
Visible on MRI MR visibility enables high precision during
treatment planning, treatment and follow-up
Fusion of CT and MR images enables high precision during
treatment planning, treatment and follow-up
Visible for minimum 2 months Remains visible during treatment and follow-up
Claim Benefit
Biocompatible Has an acceptable biological safety profile
Adaptive to surrounding tissue Low risk of tissue damage
Positionally stable during
treatment planning, treatment and follow-up Enables precise target localization during
treatment planning, treatment and follow-up
Visible on ultrasound Ultrasound guided implantation ensures higher precision of
marker placement and verification of marker location
Radiopaque, visible on X-ray (2D X-ray, fluoroscopy, CT, CBCT) Visibility on X-ray enables high precision
in treatment planning, treatment and follow-up
Fluoroscopy guided implantation ensures higher precision during
marker placement and verification of marker location
Visible on MRI MR visibility enables high precision during
treatment planning, treatment and follow-up
Fusion of CT and MR images enables high precision during
treatment planning, treatment and follow-up
Visible for minimum 2 months Remains visible during treatment and follow-up
Feature: Liquid
-
Advantages:
- Injectable with standard equipment – syringes, needles and scopes
- One injection enables placement of multiple fiducial markers
- Placement of multiple markers without re-loading
- Custom marker sizing
- Injectable with thin needles up to 25G
Feature: Highly viscous gel-like marker upon injection
-
Advantage:
- Positional stability during the planning and treatment phases
Feature: Iodine based compound
-
Advantage:
- Visibility on X-ray (kV, CT, CBCT, Fluoroscopy), MR and US
Feature: Non metallic
-
Advantages:
- Low dose perturbation in proton therapy
- Low level of artifacts