Features & benefits

The main features of BioXmark® are:

• Liquid
• Highly viscous gel-like marker upon injection
• Patented iodine compound
• Non metallic

Feature: Liquid

ClaimBenefit
Injectable with thin needles up to 25GLess risk for procedure related complications
such as bleeding and pneumothorax
Adaptable marker sizesMeeting different needs for marker sizing.
Adaptable also during implantation
Implantation of multiple markers in the same procedureLess risk of procedure related complications
Applicable in soft tissue including organs in the
thoracic, pelvic and abdominal regions
One marker to cover a wide range of cancers
such as lung, esophagus, rectum and bladder cancer
Implantable with flexible scopesImplantation with flexible scopes gives
accessibility across multiple cancer locations
Implantable with standard equipmentNo need for additional training nor for special equipment
Fast and easy implantation procedurePotential to save time

Feature: Sticky and soft iodine-based marker

ClaimBenefit
BiocompatibleHas an acceptable biological safety profile
Adaptive to surrounding tissue Low risk of tissue damage
Positionally stable during
treatment planning, treatment and follow-up
Enables precise target localization during
treatment planning, treatment and follow-up
Visible on ultrasoundUltrasound guided implantation ensures higher precision of
marker placement and verification of marker location
Radiopaque, visible on X-ray (2D X-ray, fluoroscopy, CT, CBCT)Visibility on X-ray enables high precision
in treatment planning, treatment and follow-up

Fluoroscopy guided implantation ensures higher precision during
marker placement and verification of marker location
Visible on MRIMR visibility enables high precision during
treatment planning, treatment and follow-up

Fusion of CT and MR images enables high precision during
treatment planning, treatment and follow-up
Visible for minimum 2 monthsRemains visible during treatment and follow-up

Feature: Liquid

  • Advantages:
  • Injectable with standard equipment – syringes, needles and scopes
  • One injection enables placement of multiple fiducial markers
  • Placement of multiple markers without re-loading
  • Custom marker sizing
  • Injectable with thin needles up to 25G

Feature: Highly viscous gel-like marker upon injection

  • Advantage:
  • Positional stability during the planning and treatment phases

Feature: Iodine based compound

  • Advantage:
  • Visibility on X-ray (kV, CT, CBCT, Fluoroscopy), MR and US

Feature: Non metallic

  • Advantages:
  • Low dose perturbation in proton therapy
  • Low level of artifacts