Features & benefits
The main features of BioXmark® are:
• Liquid
• Sticky and soft iodine based marker
• Non metallic

Feature: Liquid
Claim Benefit
Injectable with thin needles up to 25G Less risk for procedure related complications
such as bleeding and pneumothorax
Adaptable marker sizes Meeting different needs for marker sizing.
Adaptable also during implantation
Implantation of multiple markers in the
same procedureLess risk of procedure related complications
Applicable in soft tissue including organs
in the thoracic, pelvic and abdominal regionsOne marker to cover a wide range of cancers
such as lung, esophagus, rectum and bladder cancer
Implantable with flexible scopes Implantation with flexible scopes gives
accessibility across multiple cancer locations
Implantable with standard equipment No need for additional training nor for special equipment
Fast and easy implantation procedure Potential to save time
Feature: Sticky and soft iodine based marker
Claim Benefit
Biocompatible Has an acceptable biological safety profile
Adaptive to surrounding tissue Low risk of tissue damage
Positionally stable during
treatment planning, treatment
and follow-upEnables precise target localization during
treatment planning, treatment and follow-up
Visible on ultrasound Ultrasound guided implantation ensures higher precision of
marker placement and verification of marker location
Radiopaque, visible on X-ray
(2D X-ray, fluoroscopy, CT, CBCT)Visibility on X-ray enables high precision
in treatment planning, treatment and follow-up
Fluoroscopy guided implantation ensures higher precision during
marker placement and verification of marker location
Visible on MRI MR visibility enables high precision during
treatment planning, treatment and follow-up
Fusion of CT and MR images enables high precision during
treatment planning, treatment and follow-up
Visible for minimum 2 months Remains visible during treatment and follow-up
Feature: Non metallic
Claim Benefit
Low dose perturbation Compatible with proton radiation therapy
Low level of artifacts The low level of artifacts supports:
- Precise treatment planning and image guided treatment
- Fusion of CT and MR images
MR safe No marker displacement by MR fields
These 17 claims translate into the following main benefits of BioXmark®:
• Customizable implantation
• Positional stability and visibility
• Photon and proton radiation compatibility